Sabatie et al., 1991 - Google Patents
Biotin formation by recombinant strains of Escherichia coli: influence of the host physiologySabatie et al., 1991
- Document ID
- 2906023018596987235
- Author
- Sabatie J
- Speck D
- Reymund J
- Hebert C
- Caussin L
- Weltin D
- Gloeckler R
- O'Regan M
- Bernard S
- Ledoux C
- Ohsawa I
- Kamogawa K
- Lemoine Y
- Brown S
- Publication year
- Publication venue
- Journal of biotechnology
External Links
Snippet
Strains of Escherichia coli were transformed with different plasmids bearing the gene clusters bioXWF and bioDAYB isolated from the Gram positive bacterium Bacillus sphaericus. These genes encode for the enzymes involved in the metabolic pathway which …
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 N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 0 title abstract description 99
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