Houng et al., 1996 - Google Patents
Kinetic resolution of amino acid esters catalyzed by lipasesHoung et al., 1996
- Document ID
- 2751458763509681087
- Author
- Houng J
- Wu M
- Chen S
- Publication year
- Publication venue
- Chirality
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Snippet
Racemic amino acids were resolved by lipase via hydrolysis of their esters. Lipases (Pseudomonas lipase from Amano PS, Rhizopus lipase from Serva, and porcine pancrease lipase from Sigma) could selectively hydrolyze the L‐amino acid esters in aqueous solution …
- 239000004367 Lipase 0 title abstract description 55
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- C12P41/00—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C12P41/007—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
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- C12P13/00—Preparation of nitrogen-containing organic compounds
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- C12P41/003—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/005—Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
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- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
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