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Houng et al., 1996 - Google Patents

Kinetic resolution of amino acid esters catalyzed by lipases

Houng et al., 1996

Document ID
2751458763509681087
Author
Houng J
Wu M
Chen S
Publication year
Publication venue
Chirality

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Snippet

Racemic amino acids were resolved by lipase via hydrolysis of their esters. Lipases (Pseudomonas lipase from Amano PS, Rhizopus lipase from Serva, and porcine pancrease lipase from Sigma) could selectively hydrolyze the L‐amino acid esters in aqueous solution …
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    • C12P41/00Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture
    • C12P41/006Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
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    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/22Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/222Phenylalanine
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    • C12P41/003Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or micro-organisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
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