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Majumder et al., 2018 - Google Patents

Synthesis, characterization of novel PLGA encapsulated indole nanoparticles and study of its cytotoxic potential against A549 lung cancer cell line

Majumder et al., 2018

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Document ID
2677166781726397660
Author
Majumder S
Sharma N
Das S
Pandey N
Srivastava T
Ghosha D
Publication year
Publication venue
Journal of Applied Pharmaceutical Science

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Snippet

Objectives: Indole and its derivatives are gaining importance because of their anti-cancer activity. Here, we have reported the synthesis and characterization of novel polymeric poly D, L-lactide-co-glycolide (PLGA) indole nanoparticles, and investigated their cytotoxic …
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • A61K9/5153—Polyesters, e.g. poly(lactide-co-glycolide)
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