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Bartels et al., 2007 - Google Patents

Protective effect of antioxidative vitamins against lipid peroxidation in liver ischemia and reperfusion–an animal experimental study

Bartels et al., 2007

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Document ID
2651847262529463121
Author
Bartels M
Vilsendorf A
Kassahun T
Gerstenbergk B
Engelhart K
Vilsendorf E
Faber S
Biesalski H
Publication year
Publication venue
EXCLI J

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Ischemia and reperfusion (I/R) leads to oxidative stress with free radical formation. With respect to liver surgery and transplantation this can lead to deleterious clinical effects. Protection of the liver against I/R injury is of major concern. Thus, in this study, we examined …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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