Nothing Special   »   [go: up one dir, main page]

Waddington et al., 2018 - Google Patents

An Overhauser‐enhanced‐MRI platform for dynamic free radical imaging in vivo

Waddington et al., 2018

View PDF
Document ID
2482041429309890034
Author
Waddington D
Sarracanie M
Salameh N
Herisson F
Ayata C
Rosen M
Publication year
Publication venue
NMR in Biomedicine

External Links

Snippet

Overhauser‐enhanced MRI (OMRI) is an electron‐proton double‐resonance imaging technique of interest for its ability to non‐invasively measure the concentration and distribution of free radicals. In vivo OMRI experiments are typically undertaken at ultra‐low …
Continue reading at www.nmr.mgh.harvard.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/48—NMR imaging systems
    • G01R33/54—Signal processing systems, e.g. using pulse sequences, Generation or control of pulse sequences ; Operator Console
    • G01R33/56—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution
    • G01R33/5601—Image enhancement or correction, e.g. subtraction or averaging techniques, e.g. improvement of signal-to-noise ratio and resolution involving use of a contrast agent for contrast manipulation, e.g. a paramagnetic, super-paramagnetic, ferromagnetic or hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/34046—Volume type coils, e.g. bird-cage coils; Quadrature bird-cage coils; Circularly polarised coils
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/34—Constructional details, e.g. resonators, specially adapted to MR
    • G01R33/345—Constructional details, e.g. resonators, specially adapted to MR of waveguide type
    • G01R33/3453—Transverse electromagnetic [TEM] coils
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/32—Excitation or detection systems, e.g. using radio frequency signals
    • G01R33/36—Electrical details, e.g. matching or coupling of the coil to the receiver
    • G01R33/3628—Tuning/matching of the transmit/receive coil
    • G01R33/3635—Multi-frequency operation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/282—Means specially adapted for hyperpolarisation or for hyperpolarised contrast agents, e.g. for the generation of hyperpolarised gases using optical pumping cells, for storing hyperpolarised contrast agents or for the determination of the polarisation of a hyperpolarised contrast agent
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/30—Sample handling arrangements, e.g. sample cells, spinning mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/28—Details of apparatus provided for in groups G01R33/44 - G01R33/64
    • G01R33/38—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field
    • G01R33/381—Systems for generation, homogenisation or stabilisation of the main or gradient magnetic field using electromagnets
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/62—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/60—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using electron paramagnetic resonance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves
    • A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves involving electronic or nuclear magnetic resonance, e.g. magnetic resonance imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radiowaves
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems

Similar Documents

Publication Publication Date Title
Larson et al. Investigation of analysis methods for hyperpolarized 13C‐pyruvate metabolic MRI in prostate cancer patients
Waddington et al. An Overhauser‐enhanced‐MRI platform for dynamic free radical imaging in vivo
Coffey et al. Low-field MRI can be more sensitive than high-field MRI
Chen et al. Hyperpolarized C‐13 spectroscopic imaging of the TRAMP mouse at 3T—initial experience
Cheng et al. Automated transfer and injection of hyperpolarized molecules with polarization measurement prior to in vivo NMR
Subramanian et al. Radio frequency continuous‐wave and time‐domain EPR imaging and Overhauser‐enhanced magnetic resonance imaging of small animals: instrumental developments and comparison of relative merits for functional imaging
Epel et al. In vivo pO2 imaging of tumors: oxymetry with very low-frequency electron paramagnetic resonance
Zotev et al. Microtesla MRI with dynamic nuclear polarization
Wong et al. A system for low field imaging of laser-polarized noble gas
Afeworki et al. Three‐dimensional whole body imaging of spin probes in mice by time‐domain radiofrequency electron paramagnetic resonance
Lim et al. Construction and evaluation of a switch‐tuned 13C‐1H birdcage radiofrequency coil for imaging the metabolism of hyperpolarized 13C‐enriched compounds
Devasahayam et al. Parallel coil resonators for time-domain radiofrequency electron paramagnetic resonance imaging of biological objects
Biller et al. Imaging of nitroxides at 250 MHz using rapid-scan electron paramagnetic resonance
Serés Roig et al. Deuterium metabolic imaging of the human brain in vivo at 7 T
Coffey et al. A large volume double channel 1H–X RF probe for hyperpolarized magnetic resonance at 0.0475 T
Epel et al. Electron paramagnetic resonance oxygen imaging in vivo
Lu et al. In vitro and in vivo studies of 17O NMR sensitivity at 9.4 and 16.4 T
Massot et al. In vivo high‐resolution 3D Overhauser‐enhanced MRI in mice at 0.2 T
Coffey et al. High-resolution hyperpolarized in vivo metabolic 13C spectroscopy at low magnetic field (48.7 mT) following murine tail-vein injection
Bastiaansen et al. Probing cardiac metabolism by hyperpolarized 13 C MR using an exclusively endogenous substrate mixture and photo‐induced nonpersistent radicals
Ahn et al. Multiparametric imaging of tumor oxygenation, redox status, and anatomical structure using overhauser‐enhanced MRI–prepolarized MRI system
Sato-Akaba et al. Half-life mapping of nitroxyl radicals with three-dimensional electron paramagnetic resonance imaging at an interval of 3.6 seconds
Zhang et al. Proton/deuterium magnetic resonance imaging of rodents at 9.4 T using birdcage coils
Mouloudakis et al. Real-time polarimetry of hyperpolarized 13C nuclear spins using an atomic magnetometer
Sato-Akaba et al. Development and testing of a CW-EPR apparatus for imaging of short-lifetime nitroxyl radicals in mouse head