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Nødvig et al., 2018 - Google Patents

Efficient oligo nucleotide mediated CRISPR-Cas9 gene editing in Aspergilli

Nødvig et al., 2018

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Document ID
2474437287706086878
Author
Nødvig C
Hoof J
Kogle M
Jarczynska Z
Lehmbeck J
Klitgaard D
Mortensen U
Publication year
Publication venue
Fungal Genetics and Biology

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CRISPR-Cas9 technologies are revolutionizing fungal gene editing. Here we show that survival of specific Cas9/sgRNA mediated DNA double strand breaks (DSBs) depends on the non-homologous end-joining, NHEJ, DNA repair pathway and we use this observation to …
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