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Frame et al., 2020 - Google Patents

Fadraciclib (CYC065), a novel CDK inhibitor, targets key pro-survival and oncogenic pathways in cancer

Frame et al., 2020

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Document ID
2159978958526347166
Author
Frame S
Saladino C
MacKay C
Atrash B
Sheldrake P
McDonald E
Clarke P
Workman P
Blake D
Zheleva D
Publication year
Publication venue
Plos one

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Cyclin-dependent kinases (CDKs) contribute to the cancer hallmarks of uncontrolled proliferation and increased survival. As a result, over the last two decades substantial efforts have been directed towards identification and development of pharmaceutical CDK …
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