Nothing Special   »   [go: up one dir, main page]

Ungai-Salánki et al., 2021 - Google Patents

Single-cell adhesion strength and contact density drops in the M phase of cancer cells

Ungai-Salánki et al., 2021

View HTML
Document ID
1849101296764927183
Author
Ungai-Salánki R
Haty E
Gerecsei T
Francz B
Béres B
Sztilkovics M
Székács I
Szabó B
Horvath R
Publication year
Publication venue
Scientific Reports

External Links

Snippet

The high throughput, cost effective and sensitive quantification of cell adhesion strength at the single-cell level is still a challenging task. The adhesion force between tissue cells and their environment is crucial in all multicellular organisms. Integrins transmit force between …
Continue reading at www.nature.com (HTML) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/543—Immunoassay; Biospecific binding assay with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay
    • G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Electro-optical investigation, e.g. flow cytometers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Similar Documents

Publication Publication Date Title
Sztilkovics et al. Single-cell adhesion force kinetics of cell populations from combined label-free optical biosensor and robotic fluidic force microscopy
Bordanaba-Florit et al. Using single-vesicle technologies to unravel the heterogeneity of extracellular vesicles
Ungai-Salánki et al. Single-cell adhesion strength and contact density drops in the M phase of cancer cells
Shamah et al. Label-free cell-based assays using photonic crystal optical biosensors
US20100291575A1 (en) Detection of Changes in Cell Populations and Mixed Cell Populations
US9810683B2 (en) Use of live cell inteferometry with reflective floor of observation chamber to determine changes in mass of mammalian cells
Ansaryan et al. High-throughput spatiotemporal monitoring of single-cell secretions via plasmonic microwell arrays
Su et al. Surface plasmon resonance sensing: from purified biomolecules to intact cells
Liu et al. Real-time monitoring of single-cell secretion with a high-throughput nanoplasmonic microarray
Karandikar et al. Reagent-free and rapid assessment of T cell activation state using diffraction phase microscopy and deep learning
Han et al. Imaging technologies for microfluidic biochips
Qiu et al. Extending applications of AFM to fluidic AFM in single living cell studies
Sano et al. Microfluidic mechanotyping of a single cell with two consecutive constrictions of different sizes and an electrical detection system
Szekacs et al. Receptor specific adhesion assay for the quantification of integrin–ligand interactions in intact cells using a microplate based, label-free optical biosensor
US8703428B2 (en) Single-cell label-free assay
Horman et al. Challenges and opportunities toward enabling phenotypic screening of complex and 3D cell models
Yang et al. Deep learning image recognition-assisted atomic force microscopy for single-cell efficient mechanics in co-culture environments
Rosendahl et al. Real-time fluorescence and deformability cytometry—flow cytometry goes mechanics
Huang et al. Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow
Thal et al. Quantum dot toolbox in membrane neurotransmitter transporter research
Kolay et al. Ligand Binding-Induced Cellular Membrane Deformation is Correlated with the Changes in Membrane Stiffness
Mehrnezhad et al. Multifrequency optomechanical stiffness measurement of single adherent cells on a solid substrate with high throughput
Kovács et al. Optical sensor reveals the hidden influence of cell dissociation on adhesion measurements
Fang Label-Free Cell Phenotypic Profiling and Screening: Techniques, Experimental Design, and Data Assessment
Nagy In vitro living cell studies on high-throughput nanofluidic force microscope (FluidFM) and phase holographic imaging