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Menendez et al., 2019 - Google Patents

p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus

Menendez et al., 2019

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Document ID
18329341613654154880
Author
Menendez D
Snipe J
Marzec J
Innes C
Polack F
Caballero M
Schurman S
Kleeberger S
Resnick M
et al.
Publication year
Publication venue
The Journal of Clinical Investigation

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The Toll-like receptor 8 (TLR8) has an important role in innate immune responses to RNA viral infections, including respiratory syncytial virus (RSV). We previously reported that TLR8 expression was increased directly by the tumor suppressor and transcription factor p53 via a …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Hybridisation probes
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