Otten et al., 1972 - Google Patents
Regulation of cell growth by cyclic adenosine 3′, 5′-monophosphate: Effect of cell density and agents which alter cell growth on cyclic adenosine 3′, 5 …Otten et al., 1972
View PDF- Document ID
- 18128118206209732190
- Author
- Otten J
- Johnson G
- Pastan I
- Publication year
- Publication venue
- Journal of Biological Chemistry
External Links
Snippet
Growth stops at confluency in mouse 3T3 cells and in MA308 human diploid fibroblasts even with frequent changes of media. Accompanying this cessation of growth is an increase in the endogenous levels of cyclic adenosine 3′, 5′ monophosphate (cyclic AMP). In WI38 …
- 210000004027 cells 0 title abstract description 137
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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