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Knapp et al., 2022 - Google Patents

A longer isoform of Stim1 is a negative SOCE regulator but increases cAMP‐modulated NFAT signaling

Knapp et al., 2022

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Document ID
18107166658257568729
Author
Knapp M
Alansary D
Poth V
Förderer K
Sommer F
Zimmer D
Schwarz Y
Künzel N
Kless A
Machaca K
Helms V
Mühlhaus T
Schroda M
Lis A
Niemeyer B
Publication year
Publication venue
EMBO reports

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Alternative splicing is a potent modifier of protein function. Stromal interaction molecule 1 (Stim1) is the essential activator of store‐operated Ca2+ entry (SOCE) triggering activation of transcription factors. Here, we characterize Stim1A, a splice variant with an additional 31 …
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    • GPHYSICS
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    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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