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Hansen et al., 2013 - Google Patents

Natural RNA circles function as efficient microRNA sponges

Hansen et al., 2013

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Document ID
18079335289866274078
Author
Hansen T
Jensen T
Clausen B
Bramsen J
Finsen B
Damgaard C
Kjems J
Publication year
Publication venue
Nature

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Snippet

MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that act by direct base pairing to target sites within untranslated regions of messenger RNAs. Recently, miRNA activity has been shown to be affected by the presence of miRNA sponge …
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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