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Rodier et al., 2001 - Google Patents

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

Rodier et al., 2001

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Document ID
18052491931286689443
Author
Rodier G
Montagnoli A
Di Marcotullio L
Coulombe P
Draetta G
Pagano M
Meloche S
Publication year
Publication venue
The EMBO journal

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The activity of the cyclin‐dependent kinase inhibitor p27 is controlled by its concentration and subcellular localization. However, the mechanisms that regulate its intracellular transport are poorly understood. Here we show that p27 is phosphorylated on Ser10 in vivo …
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