Spel et al., 2020 - Google Patents
Inflammasomes contributing to inflammation in arthritisSpel et al., 2020
View PDF- Document ID
- 1742994685313737461
- Author
- Spel L
- Martinon F
- Publication year
- Publication venue
- Immunological reviews
External Links
Snippet
Inflammasomes are intracellular multiprotein signaling platforms that initiate inflammatory responses in response to pathogens and cellular damage. Active inflammasomes induce the enzymatic activity of caspase‐1, resulting in the induction of inflammatory cell death …
- 108010034143 Inflammasomes 0 title abstract description 179
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A61K38/1712—Not used, see subgroup
- A61K38/1758—Not used, see subgroup p53
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/162—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic, hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Spel et al. | Inflammasomes contributing to inflammation in arthritis | |
Kondylis et al. | The interplay of IKK, NF‐κB and RIPK 1 signaling in the regulation of cell death, tissue homeostasis and inflammation | |
Zhang et al. | NLRP3 inflammasome: checkpoint connecting innate and adaptive immunity in autoimmune diseases | |
Broderick et al. | The inflammasomes and autoinflammatory syndromes | |
Yabal et al. | Stressing out the mitochondria: Mechanistic insights into NLRP3 inflammasome activation | |
Zhao et al. | Apoptosis, autophagy, NETosis, necroptosis, and pyroptosis mediated programmed cell death as targets for innovative therapy in rheumatoid arthritis | |
Awad et al. | Inflammasome biology, molecular pathology and therapeutic implications | |
Qian et al. | Autophagy and inflammation | |
de Torre-Minguela et al. | The NLRP3 and pyrin inflammasomes: implications in the pathophysiology of autoinflammatory diseases | |
Man et al. | Regulation of inflammasome activation | |
Anders et al. | The inflammasomes in kidney disease | |
Abderrazak et al. | NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases | |
Negroni et al. | Apoptosis, necrosis, and necroptosis in the gut and intestinal homeostasis | |
Zhou et al. | Necroptosis in health and diseases | |
Razani et al. | Non‐canonical NF‐κB signaling activation and regulation: principles and perspectives | |
Nunes et al. | Cell death and inflammatory bowel diseases: apoptosis, necrosis, and autophagy in the intestinal epithelium | |
Leemans et al. | Sensing damage by the NLRP3 inflammasome | |
Cascao et al. | Effective treatment of rat adjuvant-induced arthritis by celastrol | |
Chae et al. | Advances in the understanding of familial Mediterranean fever and possibilities for targeted therapy | |
Hildebrand et al. | Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions | |
Giampietri et al. | Necroptosis: molecular signalling and translational implications | |
Caso et al. | Monogenic autoinflammatory syndromes: state of the art on genetic, clinical, and therapeutic issues | |
Malhi et al. | Hepatocyte death: a clear and present danger | |
Cordero et al. | Gain of function mutation and inflammasome driven diseases in human and mouse models | |
Fan et al. | Roles of inflammasomes in inflammatory kidney diseases |