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Beckers et al., 2003 - Google Patents

Natural, semisynthetic and synthetic microtubule inhibitors for cancer therapy

Beckers et al., 2003

Document ID
17402590690660445174
Author
Beckers T
Mahboobi S
Publication year
Publication venue
Drugs Future

External Links

Snippet

Paclitaxel, docetaxel and vinca alkaloids like vinblastine are compounds interacting with the mitotic spindle by binding to β-tubulin. They are used as therapeutics in standard chemotherapy regimens and in combination with new drugs like the HER2 targeting …
Continue reading at access.portico.org (other versions)

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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