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Tang et al., 2022 - Google Patents

Non-viral nanocarriers for CRISPR-Cas9 gene editing system delivery

Tang et al., 2022

Document ID
17229067236545051535
Author
Tang X
Wang Z
Zhang Y
Mu W
Han X
Publication year
Publication venue
Chemical Engineering Journal

External Links

Snippet

Clustered regularly interspaced short palindromic repeat-associated protein 9 (CRISPR- Cas9) is a powerful gene editing tool for treating disease. The safe and effective delivery of CRISPR-Cas9 components into cells is the premise of gene editing. The non-viral vectors …
Continue reading at www.sciencedirect.com (other versions)

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    • A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nuclic acid
    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nuclic acid the non-active part being polymeric
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