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Tormo et al., 2017 - Google Patents

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

Tormo et al., 2017

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Document ID
16927226114750826746
Author
Tormo E
Adam-Artigues A
Ballester S
Pineda B
Zazo S
González-Alonso P
Albanell J
Rovira A
Rojo F
Lluch A
Eroles P
Publication year
Publication venue
Scientific reports

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A subset of HER2+ breast cancer patients manifest clinical resistance to trastuzumab. Recently, miR-26a and miR-30b have been identified as trastuzumab response regulators, and their target gene CCNE2 seems to play an important role in resistance to trastuzumab …
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    • C12N15/1137Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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