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Li et al., 2019 - Google Patents

Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death

Li et al., 2019

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Document ID
16981851942782986870
Author
Li W
Yang J
Luo L
Jiang M
Qin B
Yin H
Zhu C
Yuan X
Zhang J
Luo Z
Du Y
Li Q
Lou Y
Qiu Y
You J
Publication year
Publication venue
Nature communications

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Snippet

Immunogenic cell death (ICD)-associated immunogenicity can be evoked through reactive oxygen species (ROS) produced via endoplasmic reticulum (ER) stress. In this study, we generate a double ER-targeting strategy to realize photodynamic therapy (PDT) …
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    • A61K47/48892—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates the conjugate being characterized by a special physical or galenical form the form being a particulate, powder, adsorbate, bead, sphere the form being a solid micro- or nanoparticle having no hollow or gas-filled core the form being a nanoparticle, e.g. an immuno-nanoparticle the material constituting the nanoparticle being a polymer
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