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Wu et al., 1989 - Google Patents

Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia.

Wu et al., 1989

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Document ID
16979081033701699289
Author
Wu D
Ugozzoli L
Pal B
Wallace R
Publication year
Publication venue
Proceedings of the National Academy of Sciences

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Snippet

A rapid nonradioactive approach to the diagnosis of sickle cell anemia is described based on an allele-specific polymerase chain reaction (ASPCR). This method allows direct detection of the normal or the sickle cell beta-globin allele in genomic DNA without …
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