Nothing Special   »   [go: up one dir, main page]

Dayon et al., 2010 - Google Patents

Combining low-and high-energy tandem mass spectra for optimized peptide quantification with isobaric tags

Dayon et al., 2010

View PDF
Document ID
16969440549373487576
Author
Dayon L
Pasquarello C
Hoogland C
Sanchez J
Scherl A
Publication year
Publication venue
Journal of proteomics

External Links

Snippet

Isobaric tagging, via TMT or iTRAQ, is widely used in quantitative proteomics. To date, tandem mass spectrometric analysis of isobarically-labeled peptides with hybrid ion trap– orbitrap (LTQ-OT) instruments has been mainly carried out with higher-energy C-trap …
Continue reading at www.academia.edu (PDF) (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or superfluid chromatograph
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/26—Mass spectrometers or separator tubes
    • H01J49/34—Dynamic spectrometers
    • H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8665—Signal analysis for calibrating the measuring apparatus
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/0027—Methods for using particle spectrometers
    • H01J49/0031—Step by step routines describing the use of the apparatus
    • H—ELECTRICITY
    • H01—BASIC ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometer or separator tubes
    • H01J49/02—Details
    • H01J49/04—Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locks; Arrangements for external adjustment of electron- or ion-optical components
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2458/00—Labels used in chemical analysis of biological material

Similar Documents

Publication Publication Date Title
Dayon et al. Combining low-and high-energy tandem mass spectra for optimized peptide quantification with isobaric tags
Fenaille et al. Data acquisition workflows in liquid chromatography coupled to high resolution mass spectrometry-based metabolomics: Where do we stand?
Gallien et al. Selectivity of LC-MS/MS analysis: implication for proteomics experiments
Wysocki et al. Mass spectrometry of peptides and proteins
US7538321B2 (en) Method of identifying substances using mass spectrometry
Stahl-Zeng et al. High sensitivity detection of plasma proteins by multiple reaction monitoring of N-glycosites
US8592752B2 (en) Techniques for performing retention-time matching of precursor and product ions and for constructing precursor and product ion spectra
US8809062B2 (en) Method and apparatus for fractionation-based chemical analyses
Wang et al. Enhanced MS/MS coverage for metabolite identification in LC-MS-based untargeted metabolomics by target-directed data dependent acquisition with time-staggered precursor ion list
US20100311176A1 (en) Method of mass analysis of target molecules in complex mixtures
US8426155B2 (en) Proteome analysis in mass spectrometers containing RF ion traps
Broeckling et al. Assigning precursor–product ion relationships in indiscriminant MS/MS data from non-targeted metabolite profiling studies
Habchi et al. How to really perform high throughput metabolomic analyses efficiently?
Weisbrod et al. Performance evaluation of a dual linear ion trap-Fourier transform ion cyclotron resonance mass spectrometer for proteomics research
Chouinard et al. Ion mobility-mass spectrometry in metabolomic, lipidomic, and proteomic analyses
CN110243985B (en) Mass spectrum detection method of biomolecules
US8507285B2 (en) Methods and devices for identifying biopolymers using mass spectroscopy
Fang et al. Quadrupole-linear ion trap tandem mass spectrometry system for clinical biomarker analysis
Walsh et al. Implementation of a data repository-driven approach for targeted proteomics experiments by multiple reaction monitoring
Schultz et al. Liquid chromatography quadrupole time-of-flight characterization of metabolites guided by the METLIN database
Li et al. Confident identification of 3-nitrotyrosine modifications in mass spectral data across multiple mass spectrometry platforms
Peterman et al. The use of a hybrid linear trap/FT-ICR mass spectrometer for on-line high resolution/high mass accuracy bottom-up sequencing
EP3287788B1 (en) Methods for mass spectrometry-based quantification using labelled compounds
Yang et al. Low mass cutoff evasion with qz value optimization in ion trap
Zhang Progress in mass spectrometry acquisition approach for quantitative proteomics