Popineau et al., 2016 - Google Patents
Novel Grb14-mediated cross talk between insulin and p62/Nrf2 pathways regulates liver lipogenesis and selective insulin resistancePopineau et al., 2016
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- 16799219324394297028
- Author
- Popineau L
- Morzyglod L
- Carré N
- Caüzac M
- Bossard P
- Prip-Buus C
- Lenoir V
- Ragazzon B
- Fauveau V
- Robert L
- Guilmeau S
- Postic C
- Komatsu M
- Canonne-Hergaux F
- Guillou H
- Burnol A
- Publication year
- Publication venue
- Molecular and Cellular Biology
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Snippet
A long-standing paradox in the pathophysiology of metabolic diseases is the selective insulin resistance of the liver. It is characterized by a blunted action of insulin to reduce glucose production, contributing to hyperglycemia, while de novo lipogenesis remains …
- 210000004185 Liver 0 title abstract description 116
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