WAN, 2014 - Google Patents
Identification and Characterization of Novel Anticoagulants from Bungarus fasciatus VenomWAN, 2014
View PDF- Document ID
- 16699198174856823728
- Author
- WAN C
- Publication year
External Links
Snippet
I would like to thank my supervisors Dr. Kang Tse Siang, Professor R Manjunatha Kini and Associate Professor Go Mei Lin for their constant encouragement and scientific input throughout my candidature. Dr Kang and Prof. Kini have provided me an opportunity to work …
- 239000003146 anticoagulant agent 0 title description 104
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Chen et al. | Fasxiator, a novel factor XIa inhibitor from snake venom, and its site‐specific mutagenesis to improve potency and selectivity | |
| AU2014301041A1 (en) | Combination therapy using a Factor XII inhibitor and a C1-Inhibitor | |
| Zhang et al. | Purification and characterization of a novel thermostable anticoagulant protein from medicinal leech Whitmania pigra Whitman | |
| Liu et al. | Anticoagulant decapeptide interacts with thrombin at the active site and exosite-I | |
| US12083170B2 (en) | Prohemostatic proteins for the treatment of bleeding | |
| US20090180995A1 (en) | Novel anticoagulant polypeptides and complex | |
| US9745363B2 (en) | Compositions and methods for inhibiting thrombogenesis | |
| WAN | Identification and Characterization of Novel Anticoagulants from Bungarus fasciatus Venom | |
| Chen et al. | Identification and characterisation of novel inhibitors on extrinsic tenase complex from Bungarus fasciatus (banded krait) venom | |
| RU2745847C2 (en) | New thrombin inhibitors | |
| US20160235824A1 (en) | Compositions and Methods for Increasing the Half-Life of Factor XA | |
| Zhu et al. | Structure-guided creation of AcAP5-derived and platelet targeted factor Xa inhibitors | |
| GIRISH | EXACTIN-A SPECIFIC INHIBTOR OF'FACTOR X'ACTIVATION BY EXTRINSIC TENASE COMPLEX ISOLATED FROM HEMACHATUS HAEMACHATUS VENOM | |
| CN114981661A (en) | Method for diagnosing fibrinolytic insufficiency associated with neutrophil extracellular traps | |
| Miller | The molecular interactions of the catalytic domain of factor XIa (FXIa): Catalysis of substrates IX and S-2366, inhibition by the Kunitz protease inhibitory domain (KPI) of Protease Nexin 2 (PN2), and binding to the surface of activated platelets | |
| Barhoover | Molecular Mechanism of Incorporation of Factor Va into Prothrombinase | |
| Wermelinger et al. | Ecotin: Exploring a feasible antithrombotic profile | |
| EA045357B1 (en) | PROHEMOSTATIC PROTEINS FOR THE TREATMENT OF BLEEDING |