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Loktev et al., 2008 - Google Patents

A BBSome subunit links ciliogenesis, microtubule stability, and acetylation

Loktev et al., 2008

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Document ID
16538989296124938886
Author
Loktev A
Zhang Q
Beck J
Searby C
Scheetz T
Bazan J
Slusarski D
Sheffield V
Jackson P
Nachury M
Publication year
Publication venue
Developmental cell

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Primary cilium dysfunction affects the development and homeostasis of many organs in Bardet-Biedl syndrome (BBS). We recently showed that seven highly conserved BBS proteins form a stable complex, the BBSome, that functions in membrane trafficking to and …
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    • GPHYSICS
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    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
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