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Alviña et al., 2010 - Google Patents

The therapeutic mode of action of 4-aminopyridine in cerebellar ataxia

Alviña et al., 2010

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Document ID
16440930807597992983
Author
Alviña K
Khodakhah K
Publication year
Publication venue
Journal of Neuroscience

External Links

Snippet

Episodic ataxia type 2 (EA2) is a hereditary cerebellar ataxia associated with mutations in the P/Q-type voltage-gated calcium (Ca2+) channels. Therapeutic approaches for treatment of EA2 are very limited. Presently, the potassium (K+) channel blocker 4-aminopyridine (4 …
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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