Saba et al., 1968 - Google Patents
Anti-heparin activity of lysosomal cationic proteins from polymorphonuclear leukocytesSaba et al., 1968
- Document ID
- 1619897984204492162
- Author
- Saba H
- Roberts H
- Herion J
- Publication year
- Publication venue
- Blood
External Links
Snippet
The lysosomal cationic proteins (LCP) of rabbit polymorphonuclear leukocytes have previously been shown to inhibit the formation of intrinsic prothrombin activator. That they also have anti-heparin activity is now demonstrated in a thrombin-plasma clotting system …
- 210000000440 Neutrophils 0 title abstract description 3
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Colucci et al. | Generation in plasma of a fast-acting inhibitor of plasminogen activator in response to endotoxin stimulation. | |
Saba et al. | Anti-heparin activity of lysosomal cationic proteins from polymorphonuclear leukocytes | |
Aberg et al. | Effect of dextran on factor VIII (antihemophilic factor) and platelet function. | |
US6566140B2 (en) | Inhibition of coagulation in blood and blood products | |
Harris et al. | Collagenases in human synovial fluid | |
Niemetz | Coagulant activity of leukocytes. Tissue factor activity | |
Fletcher et al. | Pathogenesis of the coagulation defect developing during pathological plasma proteolytic (“fibrinolytic”) states. I. The significance of fibrinogen proteolysis and circulating fibrinogen breakdown products | |
Page et al. | The cause of the blood coagulation defect following abruptio placentae | |
Contant et al. | Heparin inactivation during blood storage: its prevention by blood collection in citric acid, theophylline, adenosine, dipyridamole-CTAD mixture | |
Bellucci et al. | Platelet hyperactivation in patients with essential thrombocythemia is not associated with vascular endothelial cell damage as judged by the level of plasma thrombomodulin, protein S, PAI-1, t-PA and vWF | |
Lu et al. | Temperature dependence of plasmin-induced activation or inhibition of human platelets | |
Lipscomb et al. | Human platelets and factor XI: Localization in platelet membranes of factor XI-like activity and its functional distinction from plasma factor XI | |
Kirchhof et al. | The determination of prothrombin using synthetic chromogenic substrates; choice of a suitable activator | |
Saba et al. | The anticoagulant activity of lysosomal cationic proteins from polymorphonuclear leukocytes | |
Liebman et al. | Depression of functional and antigenic plasma antithrombin III (AT‐III) due to therapy with L‐asparaginase | |
Schipper et al. | Antithrombin III deficiency in surgical intensive care patients | |
Canoso et al. | A chlorpromazine‐induced inhibitor of blood coagulation | |
Janoff et al. | Inhibition of the elastase-like esterase in human leukocyte granules by human leukocyte cell sap | |
Abildgaard | Antithrombin–early prophecies and present challenges | |
Poon et al. | Evidence that functional subunits of antihemophilic factor (Factor VIII) are linked by noncovalent bonds | |
Zammit et al. | Interaction of immobilised unfractionated and LMW heparins with proteins in whole human plasma | |
Lalloo et al. | Coagulopathy following bites by the Papuan taipan (Oxyuranus scutellatus canni) | |
van de Putte et al. | Activators and inhibitors of fibrinolysis in rheumatoid and nonrheumatoid synovial membranes | |
Wessler et al. | On the antithrombotic action of heparin | |
Kondo et al. | Cold Activation of Complement: I. Presence of Coagulation-Related Activator |