Nothing Special   »   [go: up one dir, main page]

Cortes, 2003 - Google Patents

Supercritical anti-solvent precipitation of lactose from DMSO: A study of physical characteristics as a function of processing conditions

Cortes, 2003

Document ID
16051800631723827332
Author
Cortes A
Publication year

External Links

Snippet

Pharmaceutical industries are focused on the development of solid dosage forms of therapeutic compounds for many reasons. The advantage that the person can take the drugs in their house and leave hospital for real emergencies is the principal one. Although tablets …
Continue reading at search.proquest.com (other versions)

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/04—Solvent extraction of solutions which are liquid
    • B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids

Similar Documents

Publication Publication Date Title
EP0437451B1 (en) Finely divided solid crystalline powders via precipitation into an anti-solvent
US5707634A (en) Finely divided solid crystalline powders via precipitation into an anti-solvent
Thiering et al. Current issues relating to anti-solvent micronisation techniques and their extension to industrial scales
Reverchon Supercritical antisolvent precipitation of micro-and nano-particles
AU668367B2 (en) Formation of protein microparticles by antisolvent precipitation
Thiering et al. The influence of operating conditions on the dense gas precipitation of model proteins
Bungert et al. Separations and material processing in solutions with dense gases
Verreck et al. The effect of supercritical CO2 as a reversible plasticizer and foaming agent on the hot stage extrusion of itraconazole with EC 20 cps
US20040200774A1 (en) Method and apparatus for producing particles using supercritical fluid
Yoon et al. Tetracycline nanoparticles precipitation using supercritical and liquid CO2 as antisolvents
Vorobei et al. Using supercritical fluid technologies to prepare micro-and nanoparticles
Hong et al. Precipitation of microparticulate organic pigment powders by a supercritical antisolvent process
US7449136B2 (en) Method and apparatus for producing composite particles using supercritical fluid as plasticizing and extracting agent
JP4754830B2 (en) Apparatus and method for isolating produced particles as a suspension in a non-supercritical fluid
Xu et al. Application of supercritical carbon dioxide in the preparation of biodegradable polylactide membranes
CA2403343C (en) Process for the preparation of accelerated release formulations using compressed fluids
Bouchard et al. Selective production of polymorphs and pseudomorphs using supercritical fluid crystallization from aqueous solutions
Cortes Supercritical anti-solvent precipitation of lactose from DMSO: A study of physical characteristics as a function of processing conditions
US7767118B2 (en) Nanoparticles from supercritical fluid antisolvent process using particle growth and agglomeration retardants
US8535720B2 (en) Method and apparatus for enhanced size reduction of particles
Bouchard et al. Effect of the modifier on the particle formation and crystallisation behaviour during precipitation from aqueous solutions
Leboeuf et al. Supercritical fluid processing in food and pharmaceutical industries: Scale-up issues
RU2026670C1 (en) Method of preparing of fine-dispersed solid pharmaceutical substance
Fages Powder processing using supercritical fluids
Leboeuf et al. Current Trends of Supercritical Fluid Technology in Pharmaceutical, Nutraceutical and Food Processing Industries, 2010, 97-115 97