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Zhang et al., 2017 - Google Patents

Beneficial effects of sulforaphane treatment in Alzheimer's disease may be mediated through reduced HDAC1/3 and increased P75NTR expression

Zhang et al., 2017

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Document ID
15694862648481889806
Author
Zhang J
Zhang R
Zhan Z
Li X
Zhou F
Xing A
Jiang C
Chen Y
An L
Publication year
Publication venue
Frontiers in aging neuroscience

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Alzheimer's disease is an irreversible, progressive neurodegenerative disorder. The accumulation of Aβ in the brain is thought to play a causative role in the development of cognitive dysfunction in Alzheimer's disease. The p75 neurotrophin receptor is of great …
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    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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