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Linder et al., 2015 - Google Patents

Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome

Linder et al., 2015

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Document ID
15279321520528255630
Author
Linder B
Grozhik A
Olarerin-George A
Meydan C
Mason C
Jaffrey S
Publication year
Publication venue
Nature methods

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Snippet

Abstract N 6-methyladenosine (m6A) is the most abundant modified base in eukaryotic mRNA and has been linked to diverse effects on mRNA fate. Current mapping approaches localize m6A residues to transcript regions 100–200 nt long but cannot identify precise m6A …
Continue reading at pmc.ncbi.nlm.nih.gov (PDF) (other versions)

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    • G06F19/22—Bioinformatics, i.e. methods or systems for genetic or protein-related data processing in computational molecular biology for sequence comparison involving nucleotides or amino acids, e.g. homology search, motif or SNP [Single-Nucleotide Polymorphism] discovery or sequence alignment
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