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Martin et al., 2003 - Google Patents

Phase II study of pemetrexed in breast cancer patients pretreated with anthracyclines

Martin et al., 2003

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Document ID
1511968194924172135
Author
Martin M
Spielmann M
Namer M
Unger C
Dodwell D
Vodvarka P
Lind M
Calvert H
Casado A
Zelek L
Lluch A
Carrasco E
Kayitalire L
Zielinski C
et al.
Publication year
Publication venue
Annals of oncology

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Background To assess antitumor activity and toxicity of pemetrexed in metastatic breast cancer (MBC) patients previously treated with anthracyclines. Patients and methods Seventy- seven MBC patients from 12 European institutions were entered into the study. Seventy-two …
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    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/52Purines, e.g. adenine
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    • A61K31/7064Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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