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Duveau et al., 2011 - Google Patents

Impaired reelin processing and secretion by Cajal–Retzius cells contributes to granule cell dispersion in a mouse model of temporal lobe epilepsy

Duveau et al., 2011

Document ID
15072507441873224951
Author
Duveau V
Madhusudan A
Caleo M
Knuesel I
Fritschy J
Publication year
Publication venue
Hippocampus

External Links

Snippet

Cajal–Retzius cells play a crucial role during ontogeny in regulating cortical lamination via release of reelin. In adult brain, they comprise small calretinin‐positive interneurons located in the marginal zone of the cerebral cortex and in the hippocampal fissure. Alterations of …
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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