Pietsch et al., 1992 - Google Patents
Mitogenic Effect of Human Stem Cell Factor Alone or in Combination with G-CSF, GM-CSF, and IL-3 on Fresh Leukemic Blasts from Patients with Stem Cell Factor …Pietsch et al., 1992
- Document ID
- 14961436443484750163
- Author
- Pietsch T
- Kyas U
- Ludwig W
- Welte K
- Publication year
- Publication venue
- Cytokines in Hemopoiesis, Oncology, and AIDS II
External Links
Snippet
Recently the ligand of the myeloid surface receptor encoded by the proto-oncogene c-kit [11, 13] was identified to be a novel hematopoietic growth factor that stimulates primitive progenitor cells [12, 14]. This stem cell factor (SCF) is a multipotent hematopoietic colony …
- 206010000880 Acute myeloid leukaemia 0 title abstract description 36
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Pietsch et al. | Effects of human stem cell factor (c-kit ligand) on proliferation of myeloid leukemia cells: heterogeneity in response and synergy with other hematopoietic growth factors | |
Keller et al. | Transforming growth factor beta directly regulates primitive murine hematopoietic cell proliferation | |
Bashey et al. | Proliferative but not nonproliferative responses to granulocyte colony-stimulating factor are associated with rapid activation of the p21ras/MAP kinase signalling pathway | |
De Falco et al. | SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells | |
Nathan et al. | Human erythroid burst-forming unit: T-cell requirement for proliferation in vitro. | |
Sawada et al. | Quantitation of specific binding of erythropoietin to human erythroid colony‐forming cells | |
Debili et al. | The Mpl receptor is expressed in the megakaryocytic lineage from late progenitors to platelets | |
Jacobsen et al. | Transforming growth factor-beta trans-modulates the expression of colony stimulating factor receptors on murine hematopoietic progenitor cell lines | |
Andrews et al. | A c-kit ligand, recombinant human stem cell factor, mediates reversible expansion of multiple CD34+ colony-forming cell types in blood and marrow of baboons | |
Berdel et al. | Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit protooncogene | |
Means et al. | Erythropoietin receptors in polycythemia vera. | |
Dawson et al. | The IFN-inducible nucleoprotein IFI 16 is expressed in cells of the monocyte lineage, but is rapidly and markedly down-regulated in other myeloid precursor populations | |
Kurosawa et al. | Immobilized anti-KIT monoclonal antibody induces ligand-independent dimerization and activation of Steel factor receptor: biologic similarity with membrane-bound form of Steel factor rather than its soluble form | |
Sonoda et al. | Synergistic actions of stem cell factor and other burst-promoting activities on proliferation of CD34+ highly purified blood progenitors expressing HLA-DR or different levels of c-kit protein | |
Suzuki et al. | Comparison of the expression of IL 2 receptors by human T and B cells: induction by the polyclonal mitogens, phorbol myristate acetate, and anti-mu antibody. | |
Ashman et al. | Epitope mapping and functional studies with three monoclonal antibodies to the c‐kit receptor tyrosine kinase, YB5. B8, 17F11, and SR‐1 | |
Dai et al. | Polycythaemia vera. IV. Specific binding of stem cell factor to normal and polycythaemia vera highly purified erythroid progenitor cells | |
Pietsch et al. | Mitogenic Effect of Human Stem Cell Factor Alone or in Combination with G-CSF, GM-CSF, and IL-3 on Fresh Leukemic Blasts from Patients with Stem Cell Factor Receptor-Positive Acute Myeloid Leukemia | |
Ruscetti et al. | In vivo and in vitro Effects of TGF‐β1 on Normal and Neoplastic Haemopoiesis | |
Wendling et al. | 2 Positive and negative regulation of megakaryocytopoiesis | |
Feldman et al. | In vitro release of physically separable factors from monocytes that exert opposing effects on erythropoiesis | |
Sonoda et al. | Human FLT3 ligand acts on myeloid as well as multipotential progenitors derived from purified CD34+ blood progenitors expressing different levels of c‐kit protein | |
Sakabe et al. | Haematopoietic action of flt3 ligand on cord blood‐derived CD34‐positive cells expressing different levels of flt3 or c‐kit tyrosine kinase receptor: comparison with stem cell factor | |
Pietsch et al. | Human stem cell factor is a growth factor for myeloid leukemia cells | |
FUKUMOTO | Possible developmental interactions of hematopoietic cells and hepatocytes in fetal rat liver |