Langers et al., 2012 - Google Patents
Natural killer cells: role in local tumor growth and metastasisLangers et al., 2012
View PDF- Document ID
- 14732418350810610383
- Author
- Langers I
- Renoux V
- Thiry M
- Delvenne P
- Jacobs N
- Publication year
- Publication venue
- Biologics: targets and therapy
External Links
Snippet
Historically, the name of natural killer (NK) cells came from their natural ability to kill tumor cells in vitro. From the 1970s to date, accumulating data highlighted the importance of NK cells in host immune response against cancer and in therapy-induced antitumor response …
- 210000000822 Killer Cells, Natural 0 title abstract description 131
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues ; Not used, see subgroups
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Langers et al. | Natural killer cells: role in local tumor growth and metastasis | |
Sivori et al. | Inhibitory receptors and checkpoints in human NK cells, implications for the immunotherapy of cancer | |
Van Damme et al. | Therapeutic depletion of CCR8+ tumor-infiltrating regulatory T cells elicits antitumor immunity and synergizes with anti-PD-1 therapy | |
Souza-Fonseca-Guimaraes et al. | The emergence of natural killer cells as a major target in cancer immunotherapy | |
Pockley et al. | NK cell-based therapeutics for lung cancer | |
Smyth et al. | NKG2D function protects the host from tumor initiation | |
Chiu et al. | Acquired natural killer cell dysfunction in the tumor microenvironment of classic Hodgkin lymphoma | |
Pituch et al. | Adoptive transfer of IL13Rα2-specific chimeric antigen receptor T cells creates a pro-inflammatory environment in glioblastoma | |
Zingoni et al. | Cross-talk between activated human NK cells and CD4+ T cells via OX40-OX40 ligand interactions | |
Marcenaro et al. | Human NK cells directly recognize Mycobacterium bovis via TLR2 and acquire the ability to kill monocyte-derived DC | |
Yigit et al. | SLAMF6 as a regulator of exhausted CD8+ T cells in cancer | |
Correia et al. | Distinct human circulating NKp30+ FcεRIγ+ CD8+ T cell population exhibiting high natural killer-like antitumor potential | |
Kornacker et al. | Cytokine‐induced killer cells against autologous CLL: Direct cytotoxic effects and induction of immune accessory molecules by interferon‐γ | |
Nuebling et al. | The immune checkpoint modulator OX40 and its ligand OX40L in NK-cell immunosurveillance and acute myeloid leukemia | |
Bodduluru et al. | Natural killer cells: the journey from puzzles in biology to treatment of cancer | |
Lazarova et al. | The NKG2D axis: an emerging target in cancer immunotherapy | |
Vyas et al. | Soluble NKG2D ligands in the ovarian cancer microenvironment are associated with an adverse clinical outcome and decreased memory effector T cells independent of NKG2D downregulation | |
Miller | Biology of natural killer cells in cancer and infection: miniseries/special article | |
Attridge et al. | IL-21 Promotes CD4 T Cell Responses by Phosphatidylinositol 3-Kinase–Dependent Upregulation of CD86 on B Cells | |
Braud et al. | LLT1-CD161 interaction in cancer: promises and challenges | |
Desbois et al. | IL-15 superagonist RLI has potent immunostimulatory properties on NK cells: Implications for antimetastatic treatment | |
Wang et al. | Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy | |
Zhang et al. | The dual-functional capability of cytokine-induced killer cells and application in tumor immunology | |
Tognarelli et al. | Enhancing the activation and releasing the brakes: a double hit strategy to improve NK cell cytotoxicity against multiple myeloma | |
Onishi et al. | Immunotherapy approaches targeting regulatory T-cells |