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Van Oers et al., 2015 - Google Patents

Thirty years of baculovirus–insect cell protein expression: from dark horse to mainstream technology

Van Oers et al., 2015

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Document ID
14325144804414836386
Author
Van Oers M
Pijlman G
Vlak J
Publication year
Publication venue
Journal of General Virology

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In December 1983, a seminal paper appeared on the overexpression of human IFN-β in insect cells with a genetically engineered baculovirus. The finding that baculoviruses produced massive amounts of two proteins (polyhedrin and p10) by means of two very …
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    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N2710/14011Baculoviridae
    • C12N2710/14111Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
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