Nothing Special   »   [go: up one dir, main page]

Jiang et al., 2016 - Google Patents

Post-transcriptional modifications modulate rRNA structure and ligand interactions

Jiang et al., 2016

Document ID
14113355806579495320
Author
Jiang J
Seo H
Chow C
Publication year
Publication venue
Accounts of Chemical Research

External Links

Snippet

Conspectus Post-transcriptional modifications play important roles in modulating the functions of RNA species. The presence of modifications in RNA may directly alter its interactions with binding partners or cause structural changes that indirectly affect ligand …
Continue reading at pubs.acs.org (other versions)

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Similar Documents

Publication Publication Date Title
Jiang et al. Post-transcriptional modifications modulate rRNA structure and ligand interactions
US20220127603A1 (en) Novel crispr rna targeting enzymes and systems and uses thereof
Smola et al. Detection of RNA–protein interactions in living cells with SHAPE
Andreola et al. DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity
Yu et al. RNA-guided isomerization of uridine to pseudouridine—pseudouridylation
Mei et al. Inhibitors of protein− RNA complexation that target the RNA: specific recognition of human immunodeficiency virus type 1 TAR RNA by small organic molecules
Zheng et al. Nucleic acid oxidation in DNA damage repair and epigenetics
Khazina et al. Non-LTR retrotransposons encode noncanonical RRM domains in their first open reading frame
Dickerhoff et al. Solution structure of a MYC promoter G-quadruplex with 1: 6: 1 loop length
Vusurovic et al. Pseudoknot formation seeds the twister ribozyme cleavage reaction coordinate
van Erp et al. Conformational dynamics of DNA binding and Cas3 recruitment by the CRISPR RNA-guided cascade complex
Liu et al. Affinity-selected bicyclic peptide G-quadruplex ligands mimic a protein-like binding mechanism
Welch et al. 23S rRNA similarity from selection for peptidyl transferase mimicry
Sakakibara et al. Role of pseudouridine in structural rearrangements of helix 69 during bacterial ribosome assembly
Zhou et al. Searching the sequence space for potent aptamers using SELEX in silico
Parisien et al. Rationalization and prediction of selective decoding of pseudouridine-modified nonsense and sense codons
Gude et al. Mapping targetable sites on human telomerase RNA pseudoknot/template domain using 2′-OMe RNA-interacting polynucleotide (RIPtide) microarrays
Sousa et al. Amino acids–nucleotides biomolecular recognition: from biological occurrence to affinity chromatography
Johansson et al. Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase
Tants et al. NMR-derived secondary structure of the full-length Ox40 mRNA 3′ UTR and its multivalent binding to the immunoregulatory RBP Roquin
Barber et al. CRISPR-based peptide library display and programmable microarray self-assembly for rapid quantitative protein binding assays
Longbotham et al. Recognition of histone H3 methylation states by the PHD1 domain of histone demethylase KDM5A
Pokharel et al. High-throughput screening for functional adenosine to inosine RNA editing systems
Smoczynski et al. Advances in the Structural and Functional Understanding of m1A RNA Modification
Giannetti et al. SHAPE probing reveals human rRNAs are largely unfolded in solution