Nothing Special   »   [go: up one dir, main page]

Wanunu et al., 2009 - Google Patents

Single-molecule studies of nucleic acid interactions using nanopores

Wanunu et al., 2009

Document ID
14072103365449079258
Author
Wanunu M
Soni G
Meller A
Publication year
Publication venue
Handbook of single-molecule biophysics

External Links

Snippet

This chapter presents biophysical studies of single biopolymers using nanopores. Starting from the fundamental process of voltage-driven biopolymer translocation, the understanding of which is a prerequisite for virtually all nanopore applications, the chapter describes recent …
Continue reading at link.springer.com (other versions)

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the means of detection
    • C12Q1/6825—Nucleic acid detection involving sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for mutation or polymorphism detection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay

Similar Documents

Publication Publication Date Title
Purnell et al. Discrimination of single base substitutions in a DNA strand immobilized in a biological nanopore
Venkatesan et al. Solid-state nanopore sensors for nucleic acid analysis
Davenport et al. The role of pore geometry in single nanoparticle detection
Howorka et al. Nanopore analytics: sensing of single molecules
Meller Dynamics of polynucleotide transport through nanometre-scale pores
Dekker Solid-state nanopores
Timp et al. Nanopore sequencing: electrical measurements of the code of life
CN104011866B (en) For the nanopore sensor that biomolecule is characterized
Liu et al. Solid‐State Nanopore‐Based DNA Sequencing Technology
Wanunu Nanopores: A journey towards DNA sequencing
CN104774757B (en) Dual-pore device
Ma et al. Biological nanopores for single-molecule biophysics
Fyta Threading DNA through nanopores for biosensing applications
Yang et al. Advances in nanopore sequencing technology
US20070042366A1 (en) Nanopores, methods for using same, methods for making same and methods for characterizing biomolecules using same
Yokota et al. Electrode-embedded nanopores for label-free single-molecule sequencing by electric currents
Ding et al. Internal vs fishhook hairpin DNA: unzipping locations and mechanisms in the α-hemolysin nanopore
Heng et al. Beyond the gene chip
Jeon et al. Electrostatic control of polymer translocation speed through α-hemolysin protein pore
Mereuta et al. Nanopore-assisted, sequence-specific detection, and single-molecule hybridization analysis of short, single-stranded DNAs
Dragomir et al. Unzipping mechanism of free and polyarginine-conjugated DNA-PNA duplexes, preconfined inside the α-hemolysin nanopore
Farshad et al. Molecular dynamics simulation study of transverse and longitudinal ionic currents in solid-state nanopore DNA sequencing
Huang Nanopore-based sensing devices and applications to genome sequencing: a brief history and the missing pieces
Bahrami et al. Solid-state nanopores for biosensing with submolecular resolution
Wanunu et al. Single-molecule studies of nucleic acid interactions using nanopores