Zhou, 2021 - Google Patents
Liposome Display of Recombinant ETEC Colonization Antigens Enhances Generation of Functional Antibodies in MiceZhou, 2021
- Document ID
- 13773262818374419814
- Author
- Zhou S
- Publication year
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Snippet
Enterotoxigenic Escherichia coli (ETEC) strains colonize host intestine epithelia and initiate infectious diarrhea. The ETEC fimbriae mediating adherence to intestinal cells include colonization factor antigens (CFA), being CFA/I one the most prevalent. CFA/I is considered …
- 102000036639 antigens 0 title abstract description 53
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
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- A—HUMAN NECESSITIES
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- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
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- A61K39/02—Bacterial antigens
- A61K39/105—Delta proteobacteriales, e.g. Lawsonia; Epsilon proteobacteriales, e.g. campylobacter, helicobacter
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
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