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Chen et al., 2019 - Google Patents

Structure of the error-prone DNA ligase of African swine fever virus identifies critical active site residues

Chen et al., 2019

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Document ID
13661068094527831912
Author
Chen Y
Liu H
Yang C
Gao Y
Yu X
Chen X
Cui R
Zheng L
Li S
Li X
Ma J
Huang Z
Li J
Gan J
Publication year
Publication venue
Nature communications

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African swine fever virus (ASFV) is contagious and can cause highly lethal disease in pigs. ASFV DNA ligase (AsfvLIG) is one of the most error-prone ligases identified to date; it catalyzes DNA joining reaction during DNA repair process of ASFV and plays important …
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
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