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Smith et al., 1990 - Google Patents

Cloning and heterologous expression of the penicillin biosynthetic gene cluster from Penicillium chrysogenum

Smith et al., 1990

Document ID
13350745533695011112
Author
Smith D
Burnham M
Edwards J
Earl A
Turner G
Publication year
Publication venue
Bio/technology

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Snippet

A cosmid clone containing the putative penicillin biosynthetic gene cluster from Penicillium chrysogenum was used to transform the related filamentous fungi Neurospora crassa and Aspergillus niger, which do not produce β-lactam antibiotics. Both of the transformed hosts …
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    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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