Varone et al., 2020 - Google Patents
A novel Organ-Chip system emulates three-dimensional architecture of the human epithelia and allows fine control of mechanical forces acting on it.Varone et al., 2020
View PDF- Document ID
- 12958938998855744032
- Author
- Varone A
- Nguyen J
- Leng L
- Barrile R
- Sliz J
- Lucchesi C
- Wen N
- Gravanis A
- Hamilton G
- Karalis K
- Hinojosa C
- Publication year
- Publication venue
- bioRxiv
External Links
Snippet
Successful translation of in vivo experimental data to human patients is an unmet need and a bottleneck in the development of effective therapeutics. micro technology aims to address this need with significant advancements reported recently that enable modeling of organ …
- 210000004027 cells 0 abstract description 37
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Varone et al. | A novel organ-chip system emulates three-dimensional architecture of the human epithelia and the mechanical forces acting on it | |
Fetah et al. | The emergence of 3D bioprinting in organ-on-chip systems | |
Zakharova et al. | Multiplexed blood–brain barrier organ-on-chip | |
US11248199B2 (en) | Artificial placenta and methods of preparation | |
US20210229097A1 (en) | Vitro epithelial models comprising lamina propria-derived cells | |
US9121847B2 (en) | Three-dimensional microfluidic platforms and methods of use thereof | |
US11920116B2 (en) | Systems and methods for producing micro-engineered models of the human cervix | |
WO2018237132A1 (en) | Vascularized microfluidic platforms | |
Palaninathan et al. | Multi-organ on a chip for personalized precision medicine | |
Correia Carreira et al. | FleXert: A soft, actuatable multiwell plate insert for cell culture under stretch | |
Ko et al. | Microfluidic high-throughput 3D cell culture | |
Varone et al. | A novel Organ-Chip system emulates three-dimensional architecture of the human epithelia and allows fine control of mechanical forces acting on it. | |
CN116478819A (en) | Microfluidic system for constructing three-dimensional organ microenvironment model, and preparation method and application thereof | |
Ismayilzada et al. | Skin-on-a-chip technologies towards clinical translation and commercialization | |
US20170283778A1 (en) | Artificial peritoneal tissue and method for producing same | |
Antonio et al. | Reconstituting cytoarchitecture and function of human epithelial tissues on an open-top organ-chip | |
Huisman | Physiological vessel on chip model with integrated flow and oxygen control for in vitro small pulmonary artery studies | |
EP4273219A1 (en) | Microfluidic device | |
Sanllehí i Barceló | Development of hydrogel cavities of tuneable stiffness for the growth of epithelial crypts | |
Mendoza | Engineering in vitro Calcific Aortic Valve Disease-on-a-Chip Models | |
Bennet | Development of a microfluidic human airway-on-a-chip with cell-laden hydrogel for studying aerosol inhalation exposure with application demonstrated using whole wood smoke | |
Ali et al. | Organ on a chip | |
Chaturvedi et al. | Skin-on-Chip | |
WO2023192663A1 (en) | Rapid 3d-bioprinting of microfluidic vascular tissue models | |
Jiménez-Torres | Organotypic Approach to Study Patient-Derived Tumor Vessels |