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Anandagoda et al., 2019 - Google Patents

microRNA-142–mediated repression of phosphodiesterase 3B critically regulates peripheral immune tolerance

Anandagoda et al., 2019

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Document ID
12952882590396350324
Author
Anandagoda N
Willis J
Hertweck A
Roberts L
Jackson I
Gökmen M
Jenner R
Howard J
Lord G
et al.
Publication year
Publication venue
The Journal of clinical investigation

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Tregs play a fundamental role in immune tolerance via control of self-reactive effector T cells (Teffs). This function is dependent on maintenance of a high intracellular cAMP concentration. A number of microRNAs are implicated in the maintenance of Tregs. In this …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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