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Williams et al., 2007 - Google Patents

Mre11–Rad50–Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template

Williams et al., 2007

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Document ID
12881485821966900315
Author
Williams R
Williams J
Tainer J
Publication year
Publication venue
Biochemistry and cell biology

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The Mre11–Rad50–Nbs1 (MRN) complex is providing paradigm-shifting results of exceptional biomedical interest. MRN is among the earliest respondents to DNA double- strand breaks (DSBs), and MRN mutations cause the human cancer predisposition diseases …
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