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Ying et al., 2003 - Google Patents

BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

Ying et al., 2003

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Document ID
12764596994821493681
Author
Ying Q
Nichols J
Chambers I
Smith A
Publication year
Publication venue
Cell

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The cytokine leukemia inhibitory factor (LIF) drives self-renewal of mouse embryonic stem (ES) cells by activating the transcription factor STAT3. In serum-free cultures, however, LIF is insufficient to block neural differentiation and maintain pluripotency. Here, we report that …
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