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Inokoshi et al., 1994 - Google Patents

Cerulenin-resistant mutants of Saccharomyces cerevisiae with an altered fatty acid synthase gene

Inokoshi et al., 1994

Document ID
124123674905216068
Author
Inokoshi J
Tomoda H
Hashimoto H
Watanabe A
Takeshima H
Ōmura S
Publication year
Publication venue
Molecular and General Genetics MGG

External Links

Snippet

Cerulenin, an antifungal antibiotic produced by Cephalosporium caerulens, is a potent inhibitor of fatty acid synthase in various organisms, including Saccharomyces cerevisiae. The antibiotic inhibits the enzyme by binding covalently to the active center cysteine of the …
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