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Berns et al., 1985 - Google Patents

Presence of markers for virulence in the unique short region or repeat region or both of pseudorabies hybrid viruses

Berns et al., 1985

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Document ID
1234410264640149587
Author
Berns A
Van den Ouweland A
Quint W
Van Oirschot J
Gielkens A
Publication year
Publication venue
Journal of virology

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The unique short region and part of the repeat region of virulent pseudorabies virus strain NIA-3 was replaced by the corresponding region of the avirulent NIA-4 strain by transfection with subgenomic DNA fragments. The resulting hybrid virus showed a reduced virulence in …
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