Yu, 2021 - Google Patents
The Role of Natural Killer Cells in Gut Microbiota Mediated Pancreatic Cancer ProgressionYu, 2021
- Document ID
- 1225872646336375083
- Author
- Yu Q
- Publication year
External Links
Snippet
Pancreatic cancer is the third leading cause of cancer-related death in the United States with the lowest survival rate among all the solid cancer types. The gut microbiota, composed of trillions of microorganisms, has been shown to play an important role in pancreatic ductal …
- 210000000822 natural killer cell 0 title abstract description 214
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Hybridisation probes
- C12Q1/6883—Hybridisation probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Micro-organisms or materials therefrom
- A61K35/74—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
- G01N33/569—Immunoassay; Biospecific binding assay for micro-organisms, e.g. protozoa, bacteria, viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions involving viable micro-organisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Tomkovich et al. | Human colon mucosal biofilms from healthy or colon cancer hosts are carcinogenic | |
Derosa et al. | Intestinal Akkermansia muciniphila predicts clinical response to PD-1 blockade in patients with advanced non-small-cell lung cancer | |
Matson et al. | Cancer and the microbiome—influence of the commensal microbiota on cancer, immune responses, and immunotherapy | |
Zhang et al. | Gut microbiome directs hepatocytes to recruit MDSCs and promote cholangiocarcinoma | |
Lavoie et al. | The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response | |
Pushalkar et al. | The pancreatic cancer microbiome promotes oncogenesis by induction of innate and adaptive immune suppression | |
AU2015353465B2 (en) | Intestinal microbiota and GVHD | |
Longhi et al. | Microbiota and cancer: the emerging beneficial role of bifidobacteria in cancer immunotherapy | |
CN110582291A (en) | Reactivity marker and efficacy-improving modulator for anti-PD 1/PD-L1/PD-L2 antibody | |
Silva et al. | Microbiota and colorectal cancer: from gut to bedside | |
Dougherty et al. | Intestinal bacteria and colorectal cancer: etiology and treatment | |
Xu et al. | The role of gut microbiota in tumorigenesis and treatment | |
Andrews et al. | Concepts collide: genomic, immune, and microbial influences on the tumor microenvironment and response to cancer therapy | |
Yu et al. | Implications of the microbiome in the development and treatment of pancreatic cancer: Thinking outside of the box by looking inside the gut | |
US20220370514A1 (en) | Microbial compositions for improving the efficacy of anticancer treatments based on immune checkpoint inhibitors and/or tyrosine kinase inhibitors and markers of responsiveness to such treatments | |
Wang et al. | Intratumoral bacteria are an important “accomplice” in tumor development and metastasis | |
JP2024503710A (en) | Biological markers of intestinal dysbiosis help predict cancer patient response to anti-PD1 drugs | |
Davar et al. | Facts and hopes for gut microbiota interventions in cancer immunotherapy | |
Li et al. | Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance | |
EP3436065B1 (en) | Anti-cancer oncolytic virus combination therapies and elite responder selection platforms | |
Metwaly et al. | Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn’s disease | |
Wong et al. | Therapeutic interventions and mechanisms associated with gut microbiota-mediated modulation of immune checkpoint inhibitor responses | |
US9976149B2 (en) | Modified listeria bacteria and uses thereof | |
Yu | The Role of Natural Killer Cells in Gut Microbiota Mediated Pancreatic Cancer Progression | |
Hoskinson et al. | Elucidating the roles of the mammary and gut microbiomes in breast cancer development |