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Ke et al., 2017 - Google Patents

m6A mRNA modifications are deposited in nascent pre-mRNA and are not required for splicing but do specify cytoplasmic turnover

Ke et al., 2017

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Document ID
11941788553084432964
Author
Ke S
Pandya-Jones A
Saito Y
Fak J
Vågbø C
Geula S
Hanna J
Black D
Darnell J
Darnell R
Publication year
Publication venue
Genes & development

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Snippet

Understanding the biologic role of N 6-methyladenosine (m6A) RNA modifications in mRNA requires an understanding of when and where in the life of a pre-mRNA transcript the modifications are made. We found that HeLa cell chromatin-associated nascent pre-mRNA …
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