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Wagner et al., 2016 - Google Patents

Dose-dependent regulation of alternative splicing by MBNL proteins reveals biomarkers for myotonic dystrophy

Wagner et al., 2016

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Document ID
1182699683446043111
Author
Wagner S
Struck A
Gupta R
Farnsworth D
Mahady A
Eichinger K
Thornton C
Wang E
Berglund J
Publication year
Publication venue
PLoS genetics

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Alternative splicing is a regulated process that results in expression of specific mRNA and protein isoforms. Alternative splicing factors determine the relative abundance of each isoform. Here we focus on MBNL1, a splicing factor misregulated in the disease myotonic …
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or micro-organisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6876—Hybridisation probes
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