Wood et al., 2012 - Google Patents
A biophysical indicator of vaso-occlusive risk in sickle cell diseaseWood et al., 2012
View PDF- Document ID
- 11739757710149823485
- Author
- Wood D
- Soriano A
- Mahadevan L
- Higgins J
- Bhatia S
- Publication year
- Publication venue
- Science translational medicine
External Links
Snippet
The search for predictive indicators of disease has largely focused on molecular markers. However, biophysical markers, which can integrate multiple pathways, may provide a more global picture of pathophysiology. Sickle cell disease affects millions of people worldwide …
- 208000007056 Sickle Cell Anemia 0 title abstract description 43
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by the preceding groups
- G01N33/48—Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Detecting, measuring or recording for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING; COUNTING
- G06F—ELECTRICAL DIGITAL DATA PROCESSING
- G06F19/00—Digital computing or data processing equipment or methods, specially adapted for specific applications
- G06F19/30—Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
- G06F19/34—Computer-assisted medical diagnosis or treatment, e.g. computerised prescription or delivery of medication or diets, computerised local control of medical devices, medical expert systems or telemedicine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Wood et al. | A biophysical indicator of vaso-occlusive risk in sickle cell disease | |
US9562914B2 (en) | Microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation | |
van Noort et al. | Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling | |
Schock-Kusch et al. | Reliability of transcutaneous measurement of renal function in various strains of conscious mice | |
Selewski et al. | Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy | |
Altmann et al. | Elevated cardiac troponin I in sepsis and septic shock: no evidence for thrombus associated myocardial necrosis | |
Schlingemann et al. | VEGF levels in plasma in relation to platelet activation, glycemic control, and microvascular complications in type 1 diabetes | |
Baek et al. | Severity of acute and chronic urticaria correlates with D‐dimer level, but not C‐reactive protein or total IgE | |
Simmonds et al. | Prediction of the level and duration of shear stress exposure that induces subhemolytic damage to erythrocytes | |
US20180267021A1 (en) | Methods and devices for assessing cell properties under controlled gas environments | |
Erdoes et al. | Next generation viscoelasticity assays in cardiothoracic surgery: feasibility of the TEG6s system | |
Lu et al. | Deoxygenation reduces sickle cell blood flow at arterial oxygen tension | |
Lin et al. | Hematuria and renal outcomes in patients with diabetic chronic kidneydisease | |
Gilman et al. | Fresh and citrated whole-blood specimens can produce different thromboelastography results in patients on extracorporeal membrane oxygenation | |
Djamiatun et al. | Increase of plasminogen activator inhibitor-1 and decrease of transforming growth factor-β1 in children with dengue haemorrhagic fever in Indonesia | |
Ko et al. | Early red blood cell abnormalities as a clinical variable in sepsis diagnosis | |
Aloni et al. | Glomerular hyperfiltration is strongly correlated with age in Congolese children with sickle cell anaemia | |
Wood et al. | A biophysical marker of severity in sickle cell disease | |
US20220404334A1 (en) | Biochip having microchannel provided with capturing agent for performing cytological analysis | |
Johnson III et al. | Effect of manually preheparinized syringes on packed cell volume and total solids in blood samples collected from American alligators (Alligator mississippiensis) | |
Wołowiec et al. | Therapeutic Drug Monitoring of Direct Oral Anticoagulants in Patients with Extremely Low and High Body Weight—Pilot Study | |
Williams et al. | High-throughput quantification of red blood cell deformability and oxygen saturation to probe mechanisms of sickle cell disease | |
Nicholas | A new diagnostic tool with the potential to predict tumor metastasis | |
Chae et al. | Extracellular Water to Total Body Water Ratio in Septic Shock Patients Receiving Protocol-Driven Resuscitation Bundle Therapy | |
Oota-Ishigaki et al. | Quantitative investigation of platelet aggregation under high shear force for anti-platelet aggregation in vitro tests |