Nothing Special   »   [go: up one dir, main page]

Wood et al., 2012 - Google Patents

A biophysical indicator of vaso-occlusive risk in sickle cell disease

Wood et al., 2012

View PDF
Document ID
11739757710149823485
Author
Wood D
Soriano A
Mahadevan L
Higgins J
Bhatia S
Publication year
Publication venue
Science translational medicine

External Links

Snippet

The search for predictive indicators of disease has largely focused on molecular markers. However, biophysical markers, which can integrate multiple pathways, may provide a more global picture of pathophysiology. Sickle cell disease affects millions of people worldwide …
Continue reading at www.lmrt.mit.edu (PDF) (other versions)

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by the preceding groups
    • G01N33/48Investigating or analysing materials by specific methods not covered by the preceding groups biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Detecting, measuring or recording for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14546Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • GPHYSICS
    • G06COMPUTING; CALCULATING; COUNTING
    • G06FELECTRICAL DIGITAL DATA PROCESSING
    • G06F19/00Digital computing or data processing equipment or methods, specially adapted for specific applications
    • G06F19/30Medical informatics, i.e. computer-based analysis or dissemination of patient or disease data
    • G06F19/34Computer-assisted medical diagnosis or treatment, e.g. computerised prescription or delivery of medication or diets, computerised local control of medical devices, medical expert systems or telemedicine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases

Similar Documents

Publication Publication Date Title
Wood et al. A biophysical indicator of vaso-occlusive risk in sickle cell disease
US9562914B2 (en) Microfluidic device for real-time clinical monitoring and quantitative assessment of whole blood coagulation
van Noort et al. Novel drug candidates for the treatment of metastatic colorectal cancer through global inverse gene-expression profiling
Schock-Kusch et al. Reliability of transcutaneous measurement of renal function in various strains of conscious mice
Selewski et al. Weight-based determination of fluid overload status and mortality in pediatric intensive care unit patients requiring continuous renal replacement therapy
Altmann et al. Elevated cardiac troponin I in sepsis and septic shock: no evidence for thrombus associated myocardial necrosis
Schlingemann et al. VEGF levels in plasma in relation to platelet activation, glycemic control, and microvascular complications in type 1 diabetes
Baek et al. Severity of acute and chronic urticaria correlates with D‐dimer level, but not C‐reactive protein or total IgE
Simmonds et al. Prediction of the level and duration of shear stress exposure that induces subhemolytic damage to erythrocytes
US20180267021A1 (en) Methods and devices for assessing cell properties under controlled gas environments
Erdoes et al. Next generation viscoelasticity assays in cardiothoracic surgery: feasibility of the TEG6s system
Lu et al. Deoxygenation reduces sickle cell blood flow at arterial oxygen tension
Lin et al. Hematuria and renal outcomes in patients with diabetic chronic kidneydisease
Gilman et al. Fresh and citrated whole-blood specimens can produce different thromboelastography results in patients on extracorporeal membrane oxygenation
Djamiatun et al. Increase of plasminogen activator inhibitor-1 and decrease of transforming growth factor-β1 in children with dengue haemorrhagic fever in Indonesia
Ko et al. Early red blood cell abnormalities as a clinical variable in sepsis diagnosis
Aloni et al. Glomerular hyperfiltration is strongly correlated with age in Congolese children with sickle cell anaemia
Wood et al. A biophysical marker of severity in sickle cell disease
US20220404334A1 (en) Biochip having microchannel provided with capturing agent for performing cytological analysis
Johnson III et al. Effect of manually preheparinized syringes on packed cell volume and total solids in blood samples collected from American alligators (Alligator mississippiensis)
Wołowiec et al. Therapeutic Drug Monitoring of Direct Oral Anticoagulants in Patients with Extremely Low and High Body Weight—Pilot Study
Williams et al. High-throughput quantification of red blood cell deformability and oxygen saturation to probe mechanisms of sickle cell disease
Nicholas A new diagnostic tool with the potential to predict tumor metastasis
Chae et al. Extracellular Water to Total Body Water Ratio in Septic Shock Patients Receiving Protocol-Driven Resuscitation Bundle Therapy
Oota-Ishigaki et al. Quantitative investigation of platelet aggregation under high shear force for anti-platelet aggregation in vitro tests