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Dwight, 2014 - Google Patents

The Synthesis and Biological Activity of 2'-Fluoro-N-methanocarbathymidine Epimers and An Approach Towards the Synthesis of Morphine

Dwight, 2014

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11367956902132113264
Author
Dwight T
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In Chapter 1, the syntheses of 2'-fluoro-N-methanocarbathymidine (2'F-NMC) and arabino 2'- fluoro-N-methanocarbathymidine (ara-2'F-NMC) are detailed. The syntheses of both molecules begin with the simple precursor cyclopenten-1-one. Asymmetry is introduced into …
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    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
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    • C07F7/18—Compounds having one or more C-Si linkages as well as one or more C-O-Si linkages
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    • C07F7/1848—C1 being an unsubstituted acyclic saturated hydrocarbon radical containing less than six carbon atoms, a benzyl radical, a phenyl radical, or a methyl substituted phenyl radical
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