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Lee et al., 2019 - Google Patents

Targeting NAD+ metabolism as interventions for mitochondrial disease

Lee et al., 2019

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Document ID
11353064107172748166
Author
Lee C
Caudal A
Abell L
Nagana Gowda G
Tian R
Publication year
Publication venue
Scientific reports

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Leigh syndrome is a mitochondrial disease characterized by neurological disorders, metabolic abnormality and premature death. There is no cure for Leigh syndrome; therefore, new therapeutic targets are urgently needed. In Ndufs4-KO mice, a mouse model of Leigh …
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